Science · Uth-FastD™

The form measured in a blood test:
calcidiol.

How vitamin D travels through the body, why a blood test looks at 25(OH)D, and where Uth-FastD™ fits on that path. Every sentence comes with its source.

Last updated:

Vitamin D: why does the form matter?

Taking vitamin D is one thing, which form you take is another.

D3 (cholecalciferol), which you get from sunlight and food, is not used by the body directly. It is first converted in the liver by the enzyme 25-hydroxylase into 25(OH)D, that is, calcidiol (calcifediol). This is exactly the molecule measured as your "vitamin D level" in blood tests. The kidney then converts it into the active form, 1,25(OH)₂D. On this pathway, calcidiol is the form in which the liver conversion step is already complete. Uth-FastD™ offers calcidiol in a small, easy-to-swallow tablet made with VitamoreD™ technology. Calcidiol is not a new molecule. It is the same intermediate form that your body makes itself. That is why we describe Uth-FastD™ without big adjectives, as "the form that joins the path at a later point".

Three forms, two conversions

Why does a blood test look at 25(OH)D?

D3 stays in the blood for a short time and does not show your vitamin D status on its own. 25(OH)D stays in the blood for a long time and reflects the body's vitamin D status. That is why the test looks at this value. The active form, 1,25(OH)₂D, is tightly regulated by calcium and parathyroid hormone and is not measured routinely.[3]

Data from Türkiye

More than half of measurements below 20 ng/mL

A study of 25(OH)D measurements from 706,434 adults in 33 hospitals across 21 provinces of Türkiye found that 57.8% of measurements were below 20 ng/mL and 21.9% were in the 20–30 ng/mL range.[4] It is a hospital-based sample and does not represent the general population. A blood test is the way to find out your own level. We explain how to convert a result between ng/mL and nmol/L in the vitamin D guide.

Authorised health claims for vitamin D*

  • Vitamin D contributes to normal absorption/utilisation of calcium and phosphorus.*
  • Vitamin D contributes to normal blood calcium levels.*
  • Vitamin D contributes to the maintenance of normal bones.*
  • Vitamin D contributes to the maintenance of normal muscle function.*
  • Vitamin D contributes to the maintenance of normal teeth.*
  • Vitamin D contributes to the normal function of the immune system.*
  • Vitamin D has a role in the process of cell division.*

Source: EFSA NDA Panel[1] and the Turkish Food Codex Regulation on Nutrition and Health Claims[2]. The claims belong to the nutrient (vitamin D), not to the product.

Uth-FastD™ · VitamoreD™

A small tablet, a form further along the path

VitamoreD™ is a vitamin D technology developed in the United Kingdom. The calcidiol in Uth-FastD™ comes from a yeast-based raw material that is enriched by exposure to sunlight (UV). The tablets weigh 200 mg and are made in the United Kingdom, and every batch is tested by an independent laboratory. They come in packs of 30 and 60 tablets.

Uth-FastD™ is a food supplement, not a medicine. A blood test is the most reliable way to find out your vitamin D level. We suggest you decide on a supplement based on your test result and your physician's view.

Meet Uth-FastD™

A short glossary.

One-sentence explanations of the terms used on this page.

Calcidiol (calcifediol, 25(OH)D3)
The form of vitamin D made in the liver and measured in a blood test. Uth-FastD™ contains this form.
25(OH)D
The blood test value that shows your vitamin D level. The form measured is calcidiol.
µg (microgram)
One millionth of a gram. Very small amounts, such as vitamin D, are written in this unit.
VitamoreD™
The technology name of the calcidiol in Uth-FastD™. It was developed in the United Kingdom by Made By Daily.
Food supplement
A food used to supplement the normal diet. It is not a medicine and must not be used to diagnose, treat or prevent any disease.

Common questions.

Regular D3 (cholecalciferol) is first converted in the liver into 25(OH)D, that is, calcidiol. This is also the form measured in blood tests. On this pathway, calcidiol is the form in which the liver conversion step is already complete. Uth-FastD™ contains calcidiol.

D3 stays in the blood for a short time and does not show your vitamin D status on its own. 25(OH)D stays in the blood for a long time and reflects the body's vitamin D status. That is why the test looks at this value.

The studies we cite on this page.

The sources reflect the general scientific literature on the nutrient and forms concerned and make no product-specific clinical outcome claim.

  1. EFSA NDA Panel. Scientific Opinion on the substantiation of health claims related to vitamin D. EFSA Journal 2009;7(9):1227. https://doi.org/10.2903/j.efsa.2009.1227
  2. Turkish Food Codex Regulation on Nutrition and Health Claims and its annexed List of Health Claims (Official Gazette, in Turkish). https://www.resmigazete.gov.tr/
  3. Quesada-Gómez JM, Bouillon R. Osteoporosis International, 2018. Vitamin D metabolism and the use of 25(OH)D as a marker of vitamin D status.
  4. Gogas Yavuz D, et al. Prevalence of vitamin D deficiency and hypervitaminosis D in adult patients attending tertiary care hospitals in Türkiye, 2022. Sample of 706,434 adults from 21 provinces and 33 hospitals.

The sources reflect the official scientific assessments of the nutrient concerned and the text of the regulation. They make no product-specific clinical outcome claim.

If you would like to read more widely, our other guides are on the Longevity Insights page.

*Health claims apply when the nutrient is consumed in sufficient amounts. The information on this page is for education. Food supplements are not medicines and are not a substitute for a normal diet. The studies listed under Sources reflect the general scientific literature on the nutrient and forms concerned and make no product-specific clinical outcome claim. Pregnant women, breastfeeding mothers, people taking medicines and people with a chronic illness should consult their physician before use.